Introduction to LDA Allergen Immunotherapy


Low Dose Allergen, or LDA therapy, is a safe and effective immunotherapy used to treat food allergies and environmental allergies as well as autoimmune conditions. Injections are typically used for adults, with a sublingual option for children.

LDA treatment involves very low dose combinations of allergens along with an enzyme, beta-glucuronidase. The key component of this enzyme is that it attracts specific white blood cells (T-regulator cells) that are involved in the immune response and makes them pay attention to the allergens included with the enzyme. This causes a down-regulation or calming of the immune response. In other words, LDA works to shut off the adverse or allergenic response and has a positive effect on the immune system. This is also the reason why it works well for most autoimmune conditions where the body is attacking itself.

How Does LDA therapy Differ from Conventional Allergy Treatments?

Conventional allergy medications work on blocking the histamine response, helping only when taken (and requiring patients to take medication indefinitely). Allergy shots and allergy drops work with the immune system to gradually build tolerance to specific allergens. Not only does LDA treat multiple (over 300) foods or inhalant allergies in a single treatment, it also works to reset the immune system's response, rather than just working to build up tolerance. It also can be used for more than just allergies because of how it works to reset the immune system. LDA is less expensive and requires much less treatment - once every two months versus weekly allergy shots or daily allergy drops.

Please Note: The most important thing in treatment of allergy is not LDA. What is more important is that you should learn the causes for your problems. Then, you must learn how those causes are affecting you and what to do about them. The causes can be many-environmental, hormonal, nutritional or dietary. Remember, the cause is not necessarily always allergy! Even if your main problem is allergy, LDA is usually not the first step in management of your allergies anyway. You must have appropriate evaluation (history, physical exam and appropriate testing) to see if it is inhalant allergy, food sensitivity or chemical sensitivity. Then, the next step is to learn how to treat them with environmental changes, lifestyle changes, dietary changes and appropriate immunotherapy etc.-not LDA. It is in the later stages that Dr. Sultan may consider LDA as one of the options in treatment because of a severity of allergies or hard time managing with the above strategies. The reason we are making it fully clear is that some patients think that LDA is a blanket treatment for everything. They perceive that they must start with LDA regardless of anything else. If we don’t agree with them they get disappointed. This is wrong. Rest assured, Dr. Sultan will prescribe LDA when indicated.

Here is the pivotal point: You are coming to Dr. Sultan not for LDA. The purpose of your visit is to see what are the causes of your problems are and how to address them. 

 Please also note: LDA is seldom the first choice of treatment. You must do other things first, as pointed above before implementing LDA.

LDA Benefits Compared to Conventional Allergy Treatments:

  • Quick results (most patients see improvements within 1-3 treatments)
  • Long-lasting effects for a wide range of allergens
  • Less frequent treatments (once every 2 months initially, then less frequent)
  • Less expensive than conventional allergy therapy

Frequently Treated Conditions with LDA therapy:

  • Autoimmune Diseases: Hashimoto's Thyroiditis, Lupus (SLE), Rheumatoid Arthritis
  • Environmental Allergies, Asthma, Sinusitis
  • Food Allergies & Sensitivities
  • Severe Chemical Sensitivities
  • GI Issues: Crohn's Disease, Ulcerative Colitis
  • Lyme Disease
  • Skin Conditions: Dermatitis, Eczema, Psoriasis, Rosacea

 What does LDA therapy involve?
During an office visit, Dr. Sultan will determine if LDA is a suitable treatment for you. He will then put an order in for a specific injection. Patients will get one injection given every two months, with each treatment building on the last to restore natural immune tolerance. Gradually the interval between injections is extended until they are taken at yearly intervals. Most patients can either go a long time between injections or stop entirely after about 16 to 18 injections, with most patients noticing improvement within the first three doses.

Dr. Sultan is on a short list of practitioners trained in LDA in the United States and able to order from the only lab who compounds LDA.

 What is the cost of LDA Therapy?

Depending on your problems you may need 1,2,3 or more injections. Regardless of the number of injections the cost is $285/treatment. We charge for office visit related to LDA and there is no charge for LDA itself.

Medical insurance does not cover LDA immunotherapy itself, associated medications or the nutritional supplements required as an adjunct to LDA. You will obtain a receipt with each LDA treatment performed which will include the cost of care, any associated testing and the charge for the office visit. Office visits can be submitted to your insurance.


Office Hours
Monday:10:00 AM - 6:00 PM
Tuesday:10:00 AM - 6:00 PM
Thursday:11:00 AM - 7:00 PM
Saturday:8:00 AM - 4:00 PM



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